propr: Calculating Proportionality Between Vectors of Compositional Data
Version 3.5.1

The bioinformatic evaluation of gene co-expression often begins with correlation-based analyses. However, this approach lacks statistical validity when applied to relative data. This includes, for example, biological count data generated by high-throughput RNA-sequencing, chromatin immunoprecipitation (ChIP), ChIP-sequencing, Methyl-Capture sequencing, and other techniques. This package implements several metrics for proportionality, including phi [Lovell et al (2015) ] and rho [Erb and Notredame (2016) ]. This package also implements several metrics for differential proportionality. Unlike correlation, these measures give the same result for both relative and absolute data.

Package details

AuthorThomas Quinn [aut, cre], David Lovell [aut], Ionas Erb [aut], Anders Bilgrau [ctb], Greg Gloor [ctb]
Date of publication2018-05-09 03:43:57 UTC
MaintainerThomas Quinn <[email protected]>
Package repositoryView on CRAN
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propr documentation built on May 9, 2018, 9:04 a.m.