sctransform: Variance Stabilizing Transformations for Single Cell UMI Data

A normalization method for single-cell UMI count data using a variance stabilizing transformation. The transformation is based on a negative binomial regression model with regularized parameters. As part of the same regression framework, this package also provides functions for batch correction, and data correction. See Hafemeister and Satija 2019 <doi:10.1186/s13059-019-1874-1> for more details.

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Package details

AuthorChristoph Hafemeister [aut, cre] (<>)
MaintainerChristoph Hafemeister <>
LicenseGPL-3 | file LICENSE
Package repositoryView on CRAN
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sctransform documentation built on Jan. 13, 2021, 10:48 p.m.