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This is a method for DNA Copy Number Profiling using Next-Generation Sequencing. It has new model and test statistics based on non-homogeneous Poisson Processes with change point models. It uses an adaptation of Circular Binary Segmentation. Also included are methods for point-wise Bayesian Confidence Interval and model selection method for the change-point model. A case and a control sample reads (normal and tumor) are required.
Package details |
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Author | Jeremy J. Shen, Nancy R. Zhang |
Maintainer | Jeremy J. Shen <jeremyjshen@gmail.com> |
License | GPL-2 |
Version | 1.2.1 |
Package repository | View on CRAN |
Installation |
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