seqCBS: CN Profiling using Sequencing and CBS

This is a method for DNA Copy Number Profiling using Next-Generation Sequencing. It has new model and test statistics based on non-homogeneous Poisson Processes with change point models. It uses an adaptation of Circular Binary Segmentation. Also included are methods for point-wise Bayesian Confidence Interval and model selection method for the change-point model. A case and a control sample reads (normal and tumor) are required.

Package details

AuthorJeremy J. Shen, Nancy R. Zhang
MaintainerJeremy J. Shen <[email protected]>
Package repositoryView on CRAN
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seqCBS documentation built on May 29, 2017, 1:09 p.m.