This is a method for DNA Copy Number Profiling using Next-Generation Sequencing. It has new model and test statistics based on non-homogeneous Poisson Processes with change point models. It uses an adaptation of Circular Binary Segmentation. Also included are methods for point-wise Bayesian Confidence Interval and model selection method for the change-point model. A case and a control sample reads (normal and tumor) are required.
|Author||Jeremy J. Shen, Nancy R. Zhang|
|Date of publication||2012-10-29 08:59:40|
|Maintainer||Jeremy J. Shen <[email protected]>|
|Package repository||View on CRAN|
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