sp23design: Design and Simulation of seamless Phase II-III Clinical Trials

Provides methods for generating, exploring and executing seamless Phase II-III designs of Lai, Lavori and Shih using generalized likelihood ratio statistics. Includes pdf and source files that describe the entire R implementation with the relevant mathematical details.

AuthorBalasubramanian Narasimhan [aut, cre], Mei-Chiung Shih [aut], Pei He [aut]
Date of publication2014-06-26 00:13:09
MaintainerBalasubramanian Narasimhan <naras@stat.stanford.edu>
LicenseLGPL-3
Version0.9

View on CRAN

Functions

analyzeSP23Design Man page
computeDGivenXi Man page
computeGammaSubT Man page
computeResponseSummary Man page
executeSP23Design Man page
exploreSP23Design Man page
generateClinicalTrialData Man page
generateInterimData Man page
generateSP23Design Man page
hessian Man page
loglik1 Man page
loglik1GivenDelta Man page
loglik2 Man page
loglik2.repar0 Man page
mHP.b Man page
mHP.c Man page
performInterimLook Man page
resetSP23Design Man page
solveForCGivenABD Man page
sp23design Man page
sp23design-package Man page

Files

sp23design
sp23design/inst
sp23design/inst/examples
sp23design/inst/examples/caseC.R
sp23design/inst/examples/run9.R
sp23design/inst/examples/run6.R
sp23design/inst/examples/caseG.R
sp23design/inst/examples/run4.R
sp23design/inst/examples/run2.R
sp23design/inst/examples/run1.R
sp23design/inst/examples/run5.R
sp23design/inst/examples/caseA.R
sp23design/inst/examples/run7.R
sp23design/inst/examples/caseE.R
sp23design/inst/examples/caseF.R
sp23design/inst/examples/run3.R
sp23design/inst/examples/caseD.R
sp23design/inst/examples/run8.R
sp23design/inst/examples/caseB.R
sp23design/inst/misc
sp23design/inst/misc/sp23design.Rnw
sp23design/inst/misc/makePDF.sh
sp23design/inst/misc/makePackage.sh
sp23design/inst/misc/README.txt
sp23design/inst/misc/Phase23.bib
sp23design/inst/doc
sp23design/inst/doc/sp23design.pdf
sp23design/inst/unitTests
sp23design/inst/unitTests/runitTests.R
sp23design/inst/unitTests/runTests.R
sp23design/NAMESPACE
sp23design/Changelog
sp23design/R
sp23design/R/sp23design.R
sp23design/MD5
sp23design/DESCRIPTION
sp23design/man
sp23design/man/mHP.c.Rd sp23design/man/performInterimLook.Rd sp23design/man/solveForCGivenABD.Rd sp23design/man/generateInterimData.Rd sp23design/man/sp23design-package.Rd sp23design/man/mHP.b.Rd sp23design/man/analyzeSP23Design.Rd sp23design/man/executeSP23Design.Rd sp23design/man/computeGammaSubT.Rd sp23design/man/loglik2.Rd sp23design/man/generateClinicalTrialData.Rd sp23design/man/computeDGivenXi.Rd sp23design/man/hessian.Rd sp23design/man/loglik1GivenDelta.Rd sp23design/man/loglik1.Rd sp23design/man/computeResponseSummary.Rd sp23design/man/resetSP23Design.Rd sp23design/man/exploreSP23Design.Rd sp23design/man/generateSP23Design.Rd sp23design/man/loglik2.repar0.Rd

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