Man pages for sp23design
Design and Simulation of seamless Phase II-III Clinical Trials

analyzeSP23DesignAnalyses the results of running a design. If a trial history,...
computeDGivenXiGiven the estimates of the pi and theta, compute d.
computeGammaSubTCompute the estimate of the variance of the generalized...
computeResponseSummaryGiven interim data, compute the response end-point summary
executeSP23DesignGiven a design object, interim data and the current calendar...
exploreSP23DesignExplore a specified design by simulation
generateClinicalTrialDataA function to generate some clinical trial data according the...
generateInterimDataGenerate interim data for a clinical trial from a data set.
generateSP23DesignGenerate a seamless Phase II-III design object given some the...
hessianA utility function to compute the hessian of the generalized...
loglik1Compute the response log-likelihood
loglik1GivenDeltaComputes the constrained response log-likelihood (on the...
loglik2Computes the survival log-likelihood
loglik2.repar0Computes the constrained survival log-likelihood
mHP.bCompute the modified Haybittle-Peto boundary
mHP.cCompute the modified Haybittle-Peto boundary for the final...
performInterimLookPerform an interim look in a seamless Phase II-III clinical...
resetSP23DesignReset the design object so that counts and results are zeroed...
solveForCGivenABDA convenience function to reduce dimension by solving for one...
sp23design-packagesp23design: A package for the design, exploration and...
sp23design documentation built on May 29, 2017, 3:32 p.m.