hessian | R Documentation |
A utility function to compute the hessian of the generalized (conditional) partial likelihood ratio statistic
hessian(theta, pi, interimData)
theta |
The three-element vector (α, β, γ) |
pi |
The two-element vector (π_0, π_1) |
interimData |
The interim data frame |
Computes the hessian
A 3\times3 matrix of the hessian
Mei-Chiung Shih, Balasubramanian Narasimhan, Pei He
Lai, Tze Leung and Lavori, Philip W. and Shih, Mei-Chiung. Sequential Design of Phase II-III Cancer Trials, Statistics in Medicine, Volume 31, issue 18, p.1944-1960, 2012.
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