Man pages for sp23design
Design and Simulation of Seamless Phase II-III Clinical Trials
| analyzeSP23Design | Analyses the results of running a design. If a trial history,... |
| computeDGivenXi | Given the estimates of the pi and theta, compute d. |
| computeGammaSubT | Compute the estimate of the variance of the generalized... |
| computeResponseSummary | Given interim data, compute the response end-point summary |
| executeSP23Design | Given a design object, interim data and the current calendar... |
| exploreSP23Design | Explore a specified design by simulation |
| generateClinicalTrialData | A function to generate some clinical trial data according the... |
| generateInterimData | Generate interim data for a clinical trial from a data set. |
| generateSP23Design | Generate a seamless Phase II-III design object given some the... |
| hessian | A utility function to compute the hessian of the generalized... |
| loglik1 | Compute the response log-likelihood |
| loglik1GivenDelta | Computes the constrained response log-likelihood (on the... |
| loglik2 | Computes the survival log-likelihood |
| loglik2.repar0 | Computes the constrained survival log-likelihood |
| mHP.b | Compute the modified Haybittle-Peto boundary |
| mHP.c | Compute the modified Haybittle-Peto boundary for the final... |
| performInterimLook | Perform an interim look in a seamless Phase II-III clinical... |
| resetSP23Design | Reset the design object so that counts and results are zeroed... |
| solveForCGivenABD | A convenience function to reduce dimension by solving for one... |
| sp23design-package | sp23design: A package for the design, exploration and... |
