myeloid: Acute myeloid leukemia

Description Usage Format Details References Examples

Description

This simulated data set is based on a trial in acute myeloid leukemia.

Usage

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myeloid
data(cancer, package="survival")

Format

A data frame with 646 observations on the following 9 variables.

id

subject identifier, 1-646

trt

treatment arm A or B

sex

f=female, m=male

futime

time to death or last follow-up

death

1 if futime is a death, 0 for censoring

txtime

time to hematropetic stem cell transplant

crtime

time to complete response

rltime

time to relapse of disease

Details

This data set is used to illustrate multi-state survival curves. The correlation between within-subject event times strongly resembles that from an actual trial, but none of the actual data values are from that source.

References

Le-Rademacher JG, Peterson RA, Therneau TM, Sanford BL, Stone RM, Mandrekar SJ. Application of multi-state models in cancer clinical trials. Clin Trials. 2018 Oct; 15 (5):489-498

Examples

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coxph(Surv(futime, death) ~ trt, data=myeloid)
# See the mstate vignette for a more complete analysis

Example output

Call:
coxph(formula = Surv(futime, death) ~ trt, data = myeloid)

        coef exp(coef) se(coef)      z       p
trtB -0.3457    0.7077   0.1122 -3.081 0.00206

Likelihood ratio test=9.52  on 1 df, p=0.002029
n= 646, number of events= 320 

survival documentation built on April 26, 2021, 9:06 a.m.