apply_tci | Apply a TCI algorithm to a 'pkmod' object |
assign_pars | Set default PK parameter values Set default PK parameter... |
bayes_update | Update PK-PD model parameters using observed data values |
clc | Simulate closed-loop control |
eleveld_pd | Eleveld et al. pharmacodynamic data |
eleveld_pk | Eleveld et al. pharmacokinetic data |
elvdlpars | Get logged parameters updated in Eleveld model |
emax | Emax function |
emax_eleveld | Emax function for Eleveld (2018) model. |
emax_inv | Inverse Emax function |
emax_inv_eleveld | Inverse Emax function |
emax_inv_remi | Inverse Emax function implemented by Eleveld remifentanil... |
emax_remi | Emax function implemented by Eleveld remifentanil model |
format_pars | Format parameters for use in Rcpp functions Order parameters... |
infer_pkfn | Identify pkfn from parameter names |
inf_manual | infusion schedule |
inf_tci | Target-controlled infusion |
init_pkmod | Create an object with class "pkmod" |
init_poppkmod | Initialize a 'poppkmod' object. |
list_parnms | Identify pkfn from parameter names |
list_pkmods | Print population PK models available in 'tci' |
log_likelihood | Evaluate the log likelihood of a vector of parameter values |
log_posterior_neg | Evaluate the negative log posterior value of a parameter... |
log_prior | Calculate logged-prior probability for a set of parameters |
olc | Simulate open-loop control |
pkmod | Create a pkmod object |
pkmod1cpt | One compartment IV infusion with first-order elimination. |
pkmod2cpt | Two compartment IV infusion with first-order elimination. |
pkmod3cpt | Three compartment IV infusion with first-order elimination. |
pkmod3cptm | Solution to three-compartment IV model with effect-site |
pkmod_eleveld_ppf | Eleveld population PK model for propofol |
pkmod_eleveld_remi | Eleveld population PK model for remifentanil |
pkmod_kim | Kim population PK model for remifentanil |
pkmod_marsh | —————— Population PK and PK-PD functions... |
pkmod_minto | Minto population PK model for remifentanil |
pkmod_schnider | Schnider population PK model for propofol |
plot.sim_tci | Plot method for sim_tci class |
poppkmod | Implement a population pharmacokinetic/pharmacodynamic model. |
predict.pkmod | Predict method for pkmod objects |
predict.poppkmod | Predict method for pkmod objects |
print.pkmod | Print pkmod |
print.poppkmod | Print poppkmod |
print.sim_tci | Print method for sim_tci class |
sample_iiv | Sample PK or PK-PD parameters from the distribution of inter-... |
sample_pkmod | Sample parameters from a 'pkmod' object |
simulate_clc | Simulate closed-loop control using Bayesian updates |
simulate_olc | Simulate open-loop control using TCI |
simulate.pkmod | Simulate method for pkmod objects |
simulate.poppkmod | Summary method for 'poppkmod' objects |
simulate_tci | Simulate open- or closed-loop control |
tci_documentation | tci_documentation |
tci_effect | Effect-site TCI algorithm with plasma targeting within small... |
tci_effect_only | TCI algorithm for effect-site targeting |
tci_plasma | TCI algorithm for plasma targeting |
update.pkmod | Update method for pkmod |
validate_pkmod | pkmod validation checks |
validate_poppkmod | Perform validation checks on a 'poppkmod' object |
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