pk_oral_1cmt: Simulate PK data from a 1-compartment oral model

In vpc: Create Visual Predictive Checks

Description

Simulate PK data from a 1-compartment oral model

Usage

pk_oral_1cmt(t, tau = 24, dose = 120, ka = 1, ke = 1, cl = 10, ruv = NULL)

Arguments

t	Time after dose
tau	Dosing interval
dose	Dose
ka	Absorption rate
ke	Elimination rate
cl	Clearance
ruv	Residual variability

Value

A vector of predicted values, with or without added residual variability

Examples

dat1 <- vpc:::pk_oral_1cmt(t = c(0:72), tau = 24, dose = 120, 
                     ka = 1, ke = 1, cl = 10)
dat2 <- vpc:::pk_oral_1cmt(t = c(0:72), tau = 24, dose = 120, 
                     ka = 1, ke = 1, cl = 10, 
                     ruv = list(proportional = 0.1, additive = 0.1))

vpc documentation built on Jan. 16, 2021, 5:44 p.m.