Description Usage Arguments Value
Assumptions for this quantile quantile plot: Expected P values are uniformly distributed. Confidence intervals assume independence between tests. We expect deviations past the confidence intervals if the tests are not independent. For example, in a genome-wide association study, the genotype at any position is correlated to nearby positions. Tests of nearby genotypes will result in similar test statistics.
1 2 3 4 5 6 7 8 | pvdiv_qqplot(
ps,
effects = NULL,
ind = NULL,
ci = 0.95,
lambdaGC = FALSE,
tol = 1e-08
)
|
ps |
Numeric vector of p-values. |
effects |
a gwas effects FBM object created using 'pvdiv_standard_gwas'. Saved under the name "gwas_effects_suffix.rds" and can be loaded into R using the bigstatsr function "big_attach". |
ind |
If effects is a FBM object, this should be the row number of the phenotype from the associated metadata for the FBM object. |
ci |
Numeric. Size of the confidence interval, 0.95 by default. |
lambdaGC |
Logical. Add the Genomic Control coefficient as subtitle to the plot? |
tol |
Numeric. Tolerance for optional Genomic Control coefficient. |
A ggplot2 plot.
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