setConcsForNlme | R Documentation |
maxc
and x
to GDSC normalized-data data frame.This is run prior to running prepNlmeData. The functionality is separate because the resulting 'maxc' column might be used as a 'drug_specifier' in prepNlmeData.
setConcsForNlme(normalized_data, group_conc_ranges = F, conc_col = "CONC")
normalized_data |
a GDSC normalized-data data frame. |
group_conc_ranges |
logical. If TRUE then instances where the same drug has been used in different concentration ranges will be grouped together with a single maxc. Default is FALSE. |
conc_col |
a string to identify the column used for the concentration values - useful for combination drug treatments. |
maxc
is the maximum micromolar concentration of the treatment drug.
x
is the conversion of the micromolar screening concentration to
a range where the maximum dose = 9
removeFailedDrugs
, removeMissingDrugs
,
normalizeData
, prepNlmeData
data("gdsc_example") gdsc_example <- removeFailedDrugs(gdsc_example) gdsc_example <- removeMissingDrugs(gdsc_example) gdsc_example <- normalizeData(gdsc_example) gdsc_example <- setConcsForNlme(gdsc_example) nlme_data <- prepNlmeData(gdsc_example, "COSMIC_ID")
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.