consensusConcordants: Generate a Consensus list of Targets *[Experimental]*

In CogDisResLab/drugfindR: Investigate iLINCS for candidate repurposable drugs

Generate a Consensus list of Targets

Description

This function takes a list of (optionally split) concordance dataframes and returns a ranked list of gene or drug targets that have been chose for their maximal similarity to the signature

Usage

consensusConcordants(..., paired = FALSE, cutoff = 0.321, cellLine = NULL)

Arguments

...	One or Two (see paired) Data Frames with the concordants
paired	Logical indicating whether you split the dataframes by up and down regulated in prior analysis
cutoff	A similarity cutoff value. Defaults to 0.321
cellLine	A character vector of Cell Lines you are interested in.

Value

A tibble with the filtered and deduplicated results

Examples

TRUE

CogDisResLab/drugfindR documentation built on June 15, 2024, 9:30 p.m.