View source: R/filterSignature.R
filterSignature | R Documentation |
This function filters the L1000 Signature to a given threshold, identifying up-regulated or down-regulated or both up- and down-regulated genes
filterSignature(signature, direction = "any", threshold = NULL, prop = NULL)
signature |
A dataframe with the L1000 signature |
direction |
Direction to filter to. Must be one of "up", "down" or "any". Defaults to "any" |
threshold |
A Log Fold-Change Threshold to filter at. This can either be a single value or a vector of two values. If a single value is given, then it is assumed to be a symmetric threshold. If two values are given, then the first value is the down-regulated threshold and the second value is the up-regulated threshold. Cannot be specified with prop |
prop |
A proportion of genes to take from top and bottom. Cannot be specified with threshold |
a tibble with the filtered L1000 Signature
TRUE
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