getConcordants: Get Concordant Signatures from iLINCS *[Experimental]*

In CogDisResLab/drugfindR: Investigate iLINCS for candidate repurposable drugs

Get Concordant Signatures from iLINCS

Description

This function takes a full or filtered signature and gets concordant signatures from any of the 3 LINCS databases in iLINCS. This can get Overexpression, Knockdown or Chemical Perturbagen signatures.

Usage

getConcordants(signature, ilincsLibrary = "CP", sigDirection = NULL)

Arguments

signature	A data frame with the names of genes, their expression value and optionally their p-value
ilincsLibrary	The Library you want to search. Must be one of "OE", "KD" or "CP"
sigDirection	The direction of the signature. Must be one of "Up" or "Down" for Overexpression, Knockdown or Chemical Perturbagens

Value

A tibble with the list of concordant and discordant signatures

Examples

TRUE

CogDisResLab/drugfindR documentation built on June 15, 2024, 9:30 p.m.