View source: R/prepareSignature.R
prepareSignature | R Documentation |
This function takes a differential gene expression output from any pipeline like edgeR or DeSeq2 or any that give you the gene symbol, log_2 fold-change and p-value and transforms that into an L1000 signature for later processing.
prepareSignature(
dge,
geneColumn = "Symbol",
logfcColumn = "logFC",
pvalColumn = "PValue"
)
dge |
A dataframe-like object that has the differential gene expression information |
geneColumn |
The name of the column that has gene symbols |
logfcColumn |
The name of the column that has log_2 fold-change values |
pvalColumn |
The name of the column that has p-values |
A tibble with the L1000 signature.
TRUE
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