getSignature: Get the L1000 Signature from iLINCS *[Experimental]*

In CogDisResLab/drugfindR: Investigate iLINCS for candidate repurposable drugs

Get the L1000 Signature from iLINCS

Description

This function acts as the entrypoint to the iLINCS database. This takes in an ID and returns the signature after making a call to the iLINCS database. The default mode for drugfindR is to use L1000 signatures. However, if you are trying to retrieve a different transcriptomic signature, that is also supported by setting the l1000 parameter to FALSE.

Usage

getSignature(sigId, l1000 = TRUE)

Arguments

sigId	character. The ilincs signature_id
l1000	boolean. If you have a known l1000 signature

Value

a tibble with the L1000 Signature

Examples

## Not run: 

# Get the L1000 signature for LINCSKD_28
kd_signature <- getSignature("LINCSKD_28")

# Get the non-L1000 signature for EBI_1001
ebi_signature <- getSignature("EBI_1001")

## End(Not run)

CogDisResLab/drugfindR documentation built on June 15, 2024, 9:30 p.m.