applyQualityWeights: Apply pre-specified sample weights

In GabrielHoffman/variancePartition: Quantify and interpret drivers of variation in multilevel gene expression experiments

Apply pre-specified sample weights

Description

Apply pre-specified sample weights by scaling existing precision weights

Usage

applyQualityWeights(vobj, weights)

Arguments

vobj	EList from voom or voomWithDreamWeights.
weights	sample level weights

Details

Apply pre-specified sample-level weights to the existing precision weights estimated from the data. While the limma::voomWithQualityWeights function of Lui et al. (2015) estimates the sample-level weights from voom fit, here the weights are fixed beforehand.

References

\insertRef

liu2015weightvariancePartition

See Also

limma::voomWithQualityWeights

GabrielHoffman/variancePartition documentation built on June 19, 2024, 1:29 p.m.