SampleEdgeNew: Generate child CIF based on parent CIF

In Galaxeee/TedSim: Temporal Dynamics Simulation of scRNA-seq and CRISR/Cas9 lineage barcodes

Generate child CIF based on parent CIF

Description

Generate child CIF based on parent CIF

Usage

SampleEdgeNew(
  edge,
  depth,
  anc_state,
  edges,
  sif_mean = NULL,
  S = NULL,
  cif = NULL,
  mu = 0.1,
  p_d = 0,
  barcode = NULL,
  flag = 0,
  N_ms = NULL,
  unif_on = FALSE,
  lambda = NULL
)

Arguments

edge	current edge on the cell lineage tree
depth	current depth of the parent node
anc_state	Cell Identity Factor value of the parent node
edges	edge list of the cell lineage tree
sif_mean	state identity factor values
S	state and state identity factor of the parent
cif	cell identity factor matrix
mu	mutation rate
p_d	whether or not to have dropouts
barcode	current barcode of the parent node
flag	whether or not generate barcode along with gene expressions
N_ms	Number of possible mutated states
unif_on	if unif_on is TRUE, the mutated states will be synthetically generated using uniform distribution; otherwise, it will be sampled from a real dataset
lambda	a num vector that indicates the value of lambda that weights the additional random walk value for different depths

Galaxeee/TedSim documentation built on Oct. 2, 2022, 1:25 a.m.