simpleSimulate: Simple simulation

In Granoia/splatter-mod: Simple Simulation of Single-cell RNA Sequencing Data

Description

Simulate counts from a simple negative binomial distribution without simulated library sizes, differential expression etc.

Usage

simpleSimulate(params = newSimpleParams(), verbose = TRUE, ...)

Arguments

params	SimpleParams object containing simulation parameters.
verbose	logical. Whether to print progress messages
...	any additional parameter settings to override what is provided in params.

Details

Gene means are simulated from a gamma distribution with shape = mean.shape and rate = mean.rate. Counts are then simulated from a negative binomial distribution with mu = means and size = 1 / counts.disp. See SimpleParams for more details of the parameters.

Value

SingleCellExperiment containing simulated counts

Examples

sim <- simpleSimulate()
# Override default parameters
sim <- simpleSimulate(nGenes = 1000, nCells = 50)

Granoia/splatter-mod documentation built on May 28, 2019, 12:31 a.m.