BurdenTest: perform a case/control burden test on aggregated rare variant...

Description Usage Arguments

View source: R/shared_functions.R

Description

perform a case/control burden test on aggregated rare variant sequence data.

Usage

1
BurdenTest(mat, genes, cases, ctrls, collapse.thresh = 0, ...)

Arguments

mat

collapsing matrix data structure.

genes

list of genes to include in burden test.

cases

vector of case names.

ctrls

vector of ctrl names.

collapse.thresh

integer threshold for inclusion of sample genotype, if >0 then collapsing analyses are used, else poisson tests used (case vs. ctrl variant rate).

...

additional args for fisher.test or poisson.test


Halvee/rvatk documentation built on May 6, 2019, 10:55 p.m.