WHInit: Initialization of the W and H matrices

Description Usage Arguments Details Value

View source: R/WHInit.R

Description

Initialization of the W and H matrices.

Usage

1
WHInit(V, ...)

Arguments

V

An KxI matrix where I is the number of arrays and K is the number of probes where K should be even (K=2L).

...

Not used.

Details

The allele-specific copy number estimates are estimated using a naive genotyping algorithm. The probe-affinities are estimated using a pseudo inverse.

Value

Returns a list:

W

A Kx2 matrix of initial probe-affinity estimates.

H

A 2xI matrix of initial allele-specific copy-number estimates.

status

An integer specifying the status of the initialization: 0=normal case, 1=only one allele (either AA or BB), or 2=all samples are AB.


HenrikBengtsson/ACNE documentation built on May 6, 2019, 11:51 p.m.