robustHInit: Robust initialization of the H (copy number) matrix

In HenrikBengtsson/ACNE: Affymetrix SNP Probe-Summarization using Non-Negative Matrix Factorization

Robust initialization of the H (copy number) matrix

Description

Robust initialization of the H (copy number) matrix.

Usage

robustHInit(V, W, maxIter=5L, ...)

Arguments

V	An KxI matrix where I is the number of arrays and K is the number of probes where K should be even (K=2L).
W	A Kx2 matrix of probe-affinity estimates.
maxIter	The maximum number of iteration.
...	Not used.

Details

This function utilized a random number generator.

Value

Returns a 2xI matrix of robustified allele-specific copy-number estimates.

HenrikBengtsson/ACNE documentation built on Feb. 20, 2024, 8:20 p.m.