HenrikBengtsson/calmate: Improved Allele-Specific Copy Number of SNP Microarrays for Downstream Segmentation
The CalMaTe method calibrates preprocessed allele-specific copy number estimates (ASCNs) from DNA microarrays by controlling for single-nucleotide polymorphism-specific allelic crosstalk. The resulting ASCNs are on average more accurate, which increases the power of segmentation methods for detecting changes between copy number states in tumor studies including copy neutral loss of heterozygosity. CalMaTe applies to any ASCNs regardless of preprocessing method and microarray technology, e.g. Affymetrix and Illumina.
Getting started
Browse package contents
Package details |
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| Bioconductor views | CopyNumberVariants Genetics Microarray OneChannel SNP TwoChannel aCGH |
| Maintainer | |
| License | LGPL (>= 2.1) |
| Version | 0.13.0-9000 |
| URL | https://github.com/HenrikBengtsson/calmate/ |
| Package repository | View on GitHub |
| Installation |
Install the latest version of this package by entering the following in R:
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