hic_example_data: Example HiC dataset

Description Usage Format Value References

Description

This dataset contains HiC data from Seitan et al. (2013). The data was analysed using HOMER (Heinz et al. 2010) at a resolution of 100kb to find significant interactions. This example dataset has been filtered to retain only interactions on chromosomes 14 and 15 with a FDR < 0.1. The data has also been annotated for overlaps with Refseq promoters. See the HiC analysis vignette (vignette(package="fugi")) for more information on how this dataset was created.

Usage

1

Format

A GenomicInteractions object with length 8171.

Value

A GenomicInteractions object.

References

Seitan VC et al. (2013). Cohesin-based chromatin interactions enable regulated gene expression within pre-existing architectural compartments. Genome Res. 23, 2066-77.

Heinz S, Benner C, Spann N, Bertolino E et al. (2010). Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol. Cell 38(4), 576-589.


LTLA/fugi documentation built on June 22, 2019, 8:50 p.m.