get_prior_Gerstein: Function to build a prior using a previously built Network on...

In Luisiglm/KBoost: Inference of gene regulatory networks from gene expression data

Description

Function to build a prior using a previously built Network on ChIP-Seq.

Usage

get_prior_Gerstein(gen_names, TFs, pos_weight, neg_weight)

Arguments

gen_names	the gene names in Symbol nomenclature.
TFs	the indexes of gene names which are TFs.
pos_weight	the prior weight for edges previously found in Gerstein 2011
neg_weight	the prior weight for edges not found in the Gerstein 2011/

Value

matrix with prior probabilities of the Tf target edges.

Examples

gen_names = c("TP53","MDM2","FOXM1","ESR1","CTCF","YY1")
tfs = get_tfs_human(gen_names)
prior = get_prior_Gerstein(gen_names,tfs,0.6,0.4)

Luisiglm/KBoost documentation built on May 13, 2021, 7:27 p.m.