gwas_catalog_hits: GWAS top hits

In MRCIEU/mrQC: CheckSumStats

GWAS top hits

Description

Extract results for top hits for the trait of interest from the NHGRI-EBI GWAS catalog

Usage

gwas_catalog_hits(
  trait = NULL,
  efo = NULL,
  efo_id = NULL,
  map_association_to_study = FALSE
)

Arguments

trait	the trait of interest as reported in the GWAS catalog
efo	trait of intersest in the experimental factor ontology
efo_id	ID for trait of interest in the experimental factor ontology
map_association_to_study	map associations to study in GWAS catalog. This supports matching of results on PMID and study ancestry, which increases accuracy of comparisons, but is slow when there are large numbers of associations. It is recommended that you run this function with map_association_to_study set to FALSE. Then, if large numbers of conflicting effect sizes are identified, re-run with this argument set to TRUE. Default = FALSE.

Value

data frame

MRCIEU/mrQC documentation built on May 6, 2023, 1:40 p.m.