MartinFXP/B-NEM: Training of logical models from indirect measurements of perturbation experiments
bnem combines the use of indirect measurements of Nested Effects Models (package mnem) with the Boolean networks of CellNOptR. Perturbation experiments of signalling nodes in cells are analysed for their effect on the global gene expression profile. Those profiles give evidence for the Boolean regulation of down-stream nodes in the network, e.g., whether two parents activate their child independently (OR-gate) or jointly (AND-gate).
Getting started
Browse package contents
Package details |
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| Bioconductor views | GeneExpression GeneRegulation Network NetworkInference Pathways Preprocessing SystemsBiology |
| Maintainer | |
| License | GPL-3 |
| Version | 1.15.0 |
| URL | https://github.com/MartinFXP/bnem/ |
| Package repository | View on GitHub |
| Installation |
Install the latest version of this package by entering the following in R:
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