th_contLabelling_slope_and_partials: Analytical approximation to continuous labelling model, also...

In MorrisseyLab/CryptDriftR: Analyse crypt lineage tracing data

Description

The function returns only the slope of the monoclonal crypts and the partial clone levels.

Usage

th_contLabelling_slope_and_partials(
  mu,
  lambda,
  Ns,
  Pr = 0.5,
  alpha_beta = NULL
)

Arguments

mu	Stem cell replacement rate.
lambda	Stem cell replacement rate.
Ns	Number of functional stem cells per crypt.
Pr	Bias in stem cell replacement Pr = 0.5 is neutral.
alpha_beta	two dim vector giving rate of replacement, alternative to using Pr. The relation is beta = 2*lambda*Pr, alpha = 2*lambda*(1-Pr)

Value

A list with the slope of the monoclonal accumulation, the intercept of the monoclonal accumulation and the level of the partials.

Examples

x = th_contLabelling_slope_and_partials(mu = 1.1e-4, lambda = 0.1, Ns = 5)

MorrisseyLab/CryptDriftR documentation built on Aug. 7, 2021, 8:22 p.m.