th_contLabelling_slope_and_partials: Analytical approximation to continuous labelling model, also...

Description Usage Arguments Value Examples

View source: R/DriftFunctions.R

Description

The function returns only the slope of the monoclonal crypts and the partial clone levels.

Usage

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th_contLabelling_slope_and_partials(
  mu,
  lambda,
  Ns,
  Pr = 0.5,
  alpha_beta = NULL
)

Arguments

mu

Stem cell replacement rate.

lambda

Stem cell replacement rate.

Ns

Number of functional stem cells per crypt.

Pr

Bias in stem cell replacement Pr = 0.5 is neutral.

alpha_beta

two dim vector giving rate of replacement, alternative to using Pr. The relation is beta = 2*lambda*Pr, alpha = 2*lambda*(1-Pr)

Value

A list with the slope of the monoclonal accumulation, the intercept of the monoclonal accumulation and the level of the partials.

Examples

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x = th_contLabelling_slope_and_partials(mu = 1.1e-4, lambda = 0.1, Ns = 5)

MorrisseyLab/CryptDriftR documentation built on Aug. 7, 2021, 8:22 p.m.