contrastNBth-methods: Generate list of Wald test inference results on user...

In Nanostring-Biostats/GeoDiff: Count model based differential expression and normalization on GeoMx RNA data

Generate list of Wald test inference results on user specified contrasts

Description

Generate list of Wald test inference results including contrast estimation and p value

Usage

contrastNBth(object, ...)

## S4 method for signature 'list'
contrastNBth(
  object,
  test = c("two-sided", ">", "<"),
  method = diag(1, ncol(object$X)),
  baseline = rep(0, ncol(method))
)

Arguments

object	DE model, output by fitNBthDE or fitNBthmDE
...	additional argument list that might be used
test	type of statistical test, choose from c("two-sided", ">", "<")
method	contrasts methods, only matrix of contrast vector is allowed for now, default=diag(1,ncol(object$X)), i.e. testing the regression coefficients
baseline	testing baseline, default=0.

Value

• estimate, contrasts estimate

• wald_stat, Wald test statistics

• p_value, p value of Wald test

• se, standard error

Examples

data(NBthmDEmod2)
coeff <- contrastNBth(NBthmDEmod2)

Nanostring-Biostats/GeoDiff documentation built on April 11, 2024, 5:31 a.m.