GvHD: Extract of a Graft versus Host Disease monitoring experiment...

In RGLab/flowCore: flowCore: Basic structures for flow cytometry data

Extract of a Graft versus Host Disease monitoring experiment (Rizzieri et al., 2007)

Description

A flow cytometry high throughput screening was used to identify biomarkers that would predict the development of GvHD. The GvHD dataset is an extract of a collection of weekly peripheral blood samples obtained from patients following allogenic blood and marrow transplant. Samples were taken at various time points before and after graft.

Usage

data(GvHD)

Format

The format is an object of class flowSet composed of 35 flowFrames. Each flowFrame corresponds to one sample at one time point. The phenodata lists:

Patient

The patient Id code

Visit

The number of visits to the hospital

Days

The number of days since the graft. Negative values correpond to days before the graft.

Grade

Grade of the cancer

Details

This GvHD dataset represents the measurements of one biomarker (leukocyte) for 5 patients over 7 visits (7 time points). The blood samples were labeled with four different fluorescent probes to identify the biomarker and the fluorescent intensity was determined for at least ten thousand cells per sample.

Source

Complete dataset available at http://www.ficcs.org/software.html#Data_Files, the Flow Informatics and Computational Cytometry Society website (FICCS)

References

Rizzieri DA et al. J Clin Oncol. 2007 Jan 16; [Epub ahead of print] PMID: 17228020

RGLab/flowCore documentation built on March 19, 2024, 9:45 p.m.