# Create some data from the class `DataDual`.
plcb <- 0.001
my_data <- DataDual(
w = c(13, 77, 86, 26, 27, 36, 37, 97, 21, 49, 87, 48),
x = c(plcb, 25, 25, 25, plcb, 50, 50, 50, plcb, 100, 100, 100),
y = c(0L, 0L, 0L, 0L, 0L, 0L, 0L, 0L, 0L, 0L, 1L, 0L),
doseGrid = c(plcb, seq(25, 300, 25)),
placebo = TRUE,
ID = 1:12,
cohort = c(1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 3L, 3L, 3L, 3L)
)
# Initialize the CRM model.
my_model <- DualEndpointRW(
mean = c(0, 1),
cov = matrix(c(1, 0, 0, 1), nrow = 2),
sigma2W = c(a = 0.1, b = 0.1),
rho = c(a = 1, b = 1),
sigma2betaW = 0.01,
rw1 = TRUE
)
# Sample from the posterior distribution.
my_options <- McmcOptions(
burnin = 50,
step = 2,
samples = 4,
rng_kind = "Mersenne-Twister",
rng_seed = 1
)
samples <- mcmc(data = my_data, model = my_model, options = my_options)
samples
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