betaparametab: Estimation of Beta Parameters alpha and beta

In Yuande/MBttest: Multiple Beta t-Tests

Estimation of Beta Parameters alpha and beta

Description

parameters alpha(a) and beta (b) in beta distribution are estimated by using an iteration algorithm.

Usage

betaparametab(xn, w, P, V)

Arguments

xn	column vector, a set of library sizes.
w	column vector, a set of weights
P	proportion of counts of a gene or an isoform
V	variance for proportions of counts of a gene or an isoform over m replicate libraries in a condition

Value

return parameters a and b.

Author(s)

Yuan-De Tan [e-mail]

References

Baggerly KA, Deng L, Morris JS, Aldaz CM (2003) Differential expression in SAGE: accounting for normal between-library variation. Bioinformatics 19: 1477-1483.

See Also

betaparametVP, betaparametw

Examples

XX<-c(2000,2000,2000)
p<-0.15
V=0.004
w<-c(0.3,0.3,0.3)
betaparametab(xn=XX,w=w,P=p,V=V)
#[1] 1.145868 6.493254

Yuande/MBttest documentation built on Aug. 25, 2022, 12:58 a.m.