constructHyperexponentialSumTransitionMatrix: Model a sum of log-transformed beta-uniform mixture draws as...

In adamsardar/metaDEGth: Combining differential expression P-values in a statistically consistent fashion whilst respecting background signal/noise trends

Model a sum of log-transformed beta-uniform mixture draws as a sum of hyperexponential distributions: a phase-type distribution

Description

The distribution of a log-trasnformed beta-uniform draw is a hyperexponential distribution. The distribution of the sum of multiple such hyperexponentials does nto have a name, but can be treated as a phase-type distribution with appropriate transition matrix.

Usage

constructHyperexponentialSumTransitionMatrix(
  nValues,
  uniformProportion,
  fittedBetaShape
)

Arguments

nValues	number of values
uniformProportion	uniform proportion
fittedBetaShape	fitted beta parameter

References

https://en.wikipedia.org/wiki/Phase-type_distribution

adamsardar/metaDEGth documentation built on Sept. 28, 2022, 10:12 p.m.