g = "ISG15"
e = "ENSG00000187608"
l = "C004GD_mature neutrophil"
coords = "chr1 1012923 1013923"
cmd = "WiggleTools/wiggletools apply AUC test.bed ~/links/CB.HTS.Analysis/CTTV020/data/BLUEPRINT/C004GDH1.ERX207032.H3K27ac.bwa.GRCh38.20150528.bw"
test_chip = make_auc_matrix("data/data_blueprint_parsed_test.csv", roi, "H3K27ac", "tmp/", quantile_norm=FALSE)
blueprint_chip[[1]]$res[which(blueprint_chip[[1]]$annot$Label==l), which(roi$gene==g)]
blueprint_chip_cut[[1]]$res[which(blueprint_chip_cut[[1]]$annot$Label==l), which(roi$gene==g)]
blueprint_chip_cut_final[[1]]$res[which(blueprint_chip_cut_final[[1]]$annot$Label==l), which(roi$gene==g)]
i = which(paste(dat$donor, dat$cell_type, sep="_")==l)
y = dat$data[i]
filter(y[[1]], gene==g) %>% dplyr::select(chip_k27ac) %>% exp()
# chip data looks good, so mapping from res_1 to res_2 should be tight...
# start from all_dat
old_dat = group_by(all_dat, donor, cell_type, group) %>% nest() # group by donor / cell type
j = which(paste(old_dat$donor, old_dat$cell_type, sep="_")==l)
old_dat_1 = old_dat$data[[j]] # pick first donor / cell type
x1 = arrange(old_dat_1, gene)
y1 = arrange(y[[1]], gene)
plot(x1$chip_k27ac, y1$chip_k27ac)
blueprint_rna$res[which(paste(blueprint_rna$annot$Comment.donor.ID., blueprint_rna$annot$Characteristics.cell.type., sep="_")==l), which(colnames(blueprint_rna$res)==g)]
blueprint_rna_cut$res[which(paste(blueprint_rna_cut$annot$Comment.donor.ID., blueprint_rna_cut$annot$Characteristics.cell.type., sep="_")==l), which(colnames(blueprint_rna_cut$res)==g)]
blueprint_rna_cut_final$res[which(paste(blueprint_rna_cut_final$annot$Comment.donor.ID., blueprint_rna_cut_final$annot$Characteristics.cell.type., sep="_")==l), which(colnames(blueprint_rna_cut_final$res)==g)]
filter(y[[1]], gene==g) %>% dplyr::select(rna_response) %>% exp()
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