#' @title simulate normal distributed data
#' @description Simulate normal distributed data with spatial correlation structure
#' @usage simulateData(pi0,m,n, theta, seed = NULL, power = 0.8, alpha = 0.05)
#' @param pi0 numeric value in `[0,1]`. Proportion of true null hypothesis.
#' @param m numeric value. Number of variables.
#' @param n numeric value. Number of observations.
#' @param theta numeric value in `[0,1]`. Level of correlation between pairs of variables. See details
#' @param seed integer value. If you want to specify the seed. Default to @NULL
#' @param power numeric value in `[0,1]`. Level of power. Default 0.8.
#' @param alpha numeric value in `[0,1]`. It expresses the alpha level to control the family-wise error rate. Default 0.05.
#' @author Angela Andreella
#' @return Returns a matrix with dimensions \eqn{m \times n}.
#' @description `theta` ($\theta$) describes how rapidly the correlation declines with respect to the distance between two voxels.
#' The three-dimensional coordinates of the voxels are defined as all combinations
#' of vector $c = {1, \dots, m1/3}$, then $\Sigma_\theta = \exp(-\theta K)$ where $K$ is the matrix containing the
#' euclidean distances between the three-dimensional coordinates' voxels.
#' So, $m^{1/3}$ must be an integer value.
#' @export
#' @importFrom stats rnorm
#' @importFrom stats power.t.test
simulateSpatialData <- function(pi0,m,n, theta, seed = NULL, power = 0.8, alpha = 0.05){
if(is.null(n) & !is.null(power)){stop("Please insert sample size n")}
m0 = round(m*pi0)
m1 = round(m -m0)
if(is.null(seed)){set.seed(sample.int(1e5, 1))}else{set.seed(seed)}
pwo <- power.t.test(power = power, n=n, sig.level = alpha, type = "one.sample", alternative = "two.sided", sd = 1)
diff_mean<-pwo$delta
m3 <- round(m^(1/3),3)
if(round(m3) != m3){stop("Please insert a valid number of variables")}
simgrid_m <- expand.grid(1:m3, 1:m3, 1:m3)
distance <- as.matrix(dist(simgrid_m))
D <- chol(exp(-theta * distance))
if(is.null(seed)){set.seed(sample.int(1e5, 1))}else{set.seed(seed)}
eps <- matrix(rnorm(n * m), ncol = m) %*% D
mu <- c(rep(diff_mean,m1), rep(0, m0))
X <- matrix(rep(mu, each=n), ncol=m) + eps
return(t(X))
}
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