dafsFilterWrapper: dafsFilterWrapper Function to filter expression data within a...

Description Usage Arguments Details Value Author(s) References

Description

This function filters the expression of the supplied countData object, by invoking the dafsFilter function. dafsFilter is a filtering function used to remove rows (genes) of various expression data.

Usage

1

Arguments

cD

A countData object.

PLOT

Boolean, toggles plotting.

Details

This function filters the expression of the supplied countData object using a Data Adaptive Flag filter. The internal function (dafsFilter) uses a vector to store Kolmogorov Smirnov distance statistics, loops through cuts of the data to determine targeted K-S statistic, selects data greater than a quantile and runs Mclust on that data to determine theoretical distribution. The wrapper uses simpleFilter to determine first left-most local minima (using the Earth library).

Value

Returns an invisible filtered countData object.

Author(s)

AJ Vaestermark, JR Walters.

References

BMC Bioinformatics, 2014, 15:92


avastermark19/doseR_development documentation built on May 6, 2019, 4:31 p.m.