calcProbabilities: Calculate probability of obtaining driver gene mutation

In bastiaanvdroest/DriverProbabilities: Risk analysis of mutating driver genes

Description

Calculate probability of obtaining driver gene mutation

Usage

calcProbabilities(N, N0 = 1, mu = NULL, d = NULL, mt = NULL,
  dep = NULL, npos = NULL, perc = 0.015, psnv = NULL,
  count = NULL, invivo = F)

Arguments

N	Integer giving the generation number
N0	Integer giving the initial number of cells
mu	Integer giving the mutation rate of the cell type
d	Integer giving the doubling time of the cell type
mt	Integer giving the mitosis rate of the cell type
dep	Integer giving the depletion of mutations in the Coding Sequence
npos	Integer giving the length of the Coding Sequence
perc	Integer giving the percentage of coding sequence in whole genome
psnv	Table with the mutation spectrum from the cell type
count	Table with the number of driver gene mutations specified per mutation type

Value

Number of mutations accumulated after N generations

bastiaanvdroest/DriverProbabilities documentation built on Dec. 8, 2019, 10:29 a.m.