README.md

Ritmic

Ritmic, for RegulatIon of Tumor MIcroenvironment Composition is an R package to study the link between the gene expression in a tumor and the microenvironment composition.

The pipeline Ritmic is in 4 steps:

  1. Deconvolution of the bulk samples to obtain the cell type composition.
  2. Extraction of the cancer expression.
  3. Differential analysis of the gene expression in the cancer component.
  4. Analyze of the link between the gene expression in the cancer and the tumor composition.

This package allows to use the method. The package Ritmic_simu implements simulations to test it.

Installation

To use the package

install.packages("devtools")
devtools::install_github(https://github.com/bcm-uga/Ritmic.git)


bcm-uga/RiTMIC documentation built on June 16, 2022, 2:41 p.m.