outdegreeNormalizedFCOneMinusPScoreFunction: Outdegree normalized fold change and p-value based scoring

Description Usage Arguments Value

Description

Uses the fold change, p-values and the outdegree of the nodes to define a score function for use with computePersonalizationVectors

Usage

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outdegreeNormalizedFCOneMinusPScoreFunction(experimentalData, PPIGraph,
  extraArgs)

Arguments

experimentalData

experimentalData A data frame with as many rows as HGNC Gene Symbols, with the columns defined by the output of testFunction. The output of runTestOnData.

PPIGraph

PPIGraph A list containing igraph_object - the igraph object and vertex_map - a frame containing node attributes currently indegree and outdegree. The output of createIGraphObject

extraArgs

NA

Value

A data frame with two columns npv - normal personalization vector and dpv - disease personalization vector. There are as many rows as number of HGNC Symbols in PPIGraph


bhatturam/prius documentation built on May 12, 2019, 8:24 p.m.