biobakery/MACARRoN: Prioritization of potentially bioactive metabolic features from epidemiological and environmental metabolomics datasets

Macarron is a workflow for the prioritization of potentially bioactive metabolites from metabolomics experiments. Prioritization integrates strengths of evidences of bioactivity such as covariation with a known metabolite, abundance relative to a known metabolite and association with an environmental or phenotypic indicator of bioactivity. Broadly, the workflow consists of stratified clustering of metabolic spectral features which co-vary in abundance in a condition, transfer of functional annotations, estimation of relative abundance and differential abundance analysis to identify associations between features and phenotype/condition.

Getting started

Package details

Bioconductor views Clustering Coverage FunctionalPrediction Metabolomics Sequencing
Maintainer
LicenseMIT + file LICENSE
Version1.9.1
URL http://huttenhower.sph.harvard.edu/macarron
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("biobakery/MACARRoN")
biobakery/MACARRoN documentation built on July 1, 2024, 10:01 p.m.