calculate_gene_lfc: Calculate gene log fold changes.

In cancerit/RCRISPR: R Functions for CRISPR-Related Analyses

Calculate gene log fold changes.

Description

Calculate gene log fold changes.

Usage

calculate_gene_lfc(
  data = NULL,
  id_column = 1,
  gene_column = 2,
  sample_columns = NULL
)

Arguments

data	sample sgRNA fold change matrix.
id_column	the index of column containing unique sgRNA identifiers.
gene_column	the index of column containing gene symbols.
sample_columns	the index of columns containing sample data to process.

Details

Takes an sgRNA fold change matrix and averages by gene.

Requires column indices be defined:

• id_column - column containing guide (sgRNA) identifiers (Default = 1).

• gene_column - column containing gene symbols/identifiers (Default = 2).

Value

a data frame containing sample gene-level log fold changes.

cancerit/RCRISPR documentation built on April 26, 2023, 10:12 p.m.