initial.guess.alpha: Calculate initial alpha values (labeled RNA) by closed form...

Description Usage Arguments Value Author(s)

Description

Calculate initial alpha values (labeled RNA) by closed form solution

Usage

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initial.guess.alpha(N = 1, L, counts, gene.names = rownames(counts),
  seq.depths, cross.cont, labeled.samples,
  total.samples = c(1:length(seq.depths)[-labeled.samples]))

Arguments

N

number of cells

L

length of genes

counts

count table for genes (rows) and samples (columns)

gene.names

names of features == rownames of count table for which the initial guess should be calculated

seq.depths

vector with sequencing depths for each sample

cross.cont

vector with cross contamination rates for each sample

labeled.samples

numeric vector indicating which of the samples are labeled RNA

total.samples

numeric vector indicating which of the samples are total RNA

Value

initial guess for alpha for given genes

Author(s)

Carina Demel


carinademel/RNAlife documentation built on May 13, 2019, 12:43 p.m.