cbg-ethz/nempi: Inferring unobserved perturbations from gene expression data

Takes as input an incomplete perturbation profile and differential gene expression in log odds and infers unobserved perturbations and augments observed ones. The inference is done by iteratively inferring a network from the perturbations and inferring perturbations from the network. The network inference is done by Nested Effects Models.

Getting started

Package details

Bioconductor views ATACSeq CRISPR Classification DNASeq DifferentialExpression DifferentialMethylation GeneExpression GeneSignaling Network NetworkInference NeuralNetwork Pathways PooledScreens RNASeq SingleCell Software SystemsBiology
URL https://github.com/cbg-ethz/nempi/
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
cbg-ethz/nempi documentation built on Dec. 26, 2021, 12:10 a.m.