cbg-ethz/pcNEM: Probabilistic combinatorial nested effects model
The package 'pcnem' allows to reconstruct networks from probabilistically modelled combinatorial perturbations. It takes as input (1.) a set of pathway components, which were perturbed, (2.) a perturbation map defining the perturbation probabilities of each component, and (3.) phenotypic readout of these perturbations (e.g. gene expression, protein expression). The output is a directed acyclic graph representing the phenotypic hierarchy.
Browse package contents
Package details |
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| Author | Sumana Srivatsa, Niko Beerenwinkel |
| Bioconductor views | Bioinformatics GraphsAndNetworks Microarray NetworkInference Pathways SystemsBiology |
| Maintainer | Sumana Srivatsa <sumana.srivatsa@bsse.ethz.ch> |
| License | GPL (>= 2) |
| Version | 2.46.0 |
| URL | http://www.bioconductor.org |
| Package repository | View on GitHub |
| Installation |
Install the latest version of this package by entering the following in R:
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