coefVar: Calculating the coefficient of variation by utilizing...

In crukci-bioinformatics/qPLEXanalyzer: Tools for quantitative proteomics data analysis

Calculating the coefficient of variation by utilizing expression data within individual sample groups.

Description

Calculating the coefficient of variation by utilizing peptide/protein expression data within individual sample groups.

Usage

coefVar(MSnSetObj)

Arguments

MSnSetObj

MSnSet; an object of class MSnSet

Details

In this approach, we calculate distributions of the coefficient of variation (CV) for the dataset. The CVs are determined based on peptides or proteins intensities within each sample group, and the results are visualized through boxplots and cumulative fraction plots for each sample group.

Value

An object of class list consisting of object of class ggplot)

Examples

data(human_anno)
data(exp3_OHT_ESR1)
MSnSet_data <- convertToMSnset(exp3_OHT_ESR1$intensities_qPLEX1, 
                               metadata=exp3_OHT_ESR1$metadata_qPLEX1,
                               indExpData=c(7:16), 
                               Sequences=2, 
                               Accessions=6)
exprs(MSnSet_data) <- exprs(MSnSet_data)+1.1                                 
res <- coefVar(MSnSet_data)                             

crukci-bioinformatics/qPLEXanalyzer documentation built on Sept. 24, 2024, 1:13 a.m.