hmmpickr-package: Pick a ChromHMM model

In csiu/hmmpickr: Pick a ChromHMM model

Description

Select the ChromHMM model that is most well-defined.

Details

ChromHMM (Ernst & Kellis, 2012), an implementation of a hidden Markov model (HMM), uses epigenetic features such as histone modifications to represent observed (or output) states and unobserved (or hidden) states to represent chromatin states. Due to the nature of hidden states, the number of states will need to be specified programmatically and oftentimes numerous candidate models are generated. The goal of hmmpickr is to help pick the model whose states are the most well-defined.

Author(s)

Celia Siu

Maintainer: Celia Siu <[e-mail]>

Examples

library(hmmpickr)

# List of ChromHMM models
model_files <- c(
  system.file("extdata", "model_roadmap15.txt", package="hmmpickr"),
  system.file("extdata", "model_roadmap18.txt", package="hmmpickr"))

# Calculate homogeneity cost
hmmpick(model_files, full_path = FALSE)

csiu/hmmpickr documentation built on May 14, 2019, 12:24 p.m.