Estep2ByGene: E-step with Gauss–Legendre quadrature approximation

In cz-ye/DECENT: Differential Expression with Capture Efficiency adjustmeNT

E-step with Gauss–Legendre quadrature approximation

Description

Perform E-step for one gene, with GQ approximation

Usage

Estep2ByGene(par, z, sf, pi0, mu, disp, k, b, GQ.object)

Arguments

par	A matrix with two columns containing coefficient for the dropout model. The second column is currently unused and set to zero but may be used in the future to model droput rates dependence on gene-specific factors.
z	vector of observed count
sf	Size factors for different cells
pi0	gene-specific zero-inflated parameter
mu	gene-specific mean parameter
disp	Reciprocal of gene-specific size parameter for
GQ.object	Gauss-Legendre quadrature points and weights

cz-ye/DECENT documentation built on Jan. 25, 2023, 5:57 a.m.