getImputed: Get imputed data

In cz-ye/DECENT: Differential Expression with Capture Efficiency adjustmeNT

Get imputed data

Description

Get mean imputed data by running E-step once without GQ approximation using the LRT estimates.

Usage

getImputed(data.obs, par.est, sf, CE, XW, tau, parallel = T)

Arguments

data.obs	Observed count matrix for endogeneous genes, rows represent genes, columns represent cells
par.est	LRT estimates, using par.DE by default
sf	A vector containing size factors for all cells
CE	A vector containing capture efficiencies for all cells
XW	A matrix containing information for X (cell-type) and W (other covariates)
tau	cell-specific estimates (intcp,slope) that link Beta-Binomial dispersion parameter to the mean expression.
parallel	If TRUE, run in parallel

Value

A matrix containing the mean imputed data.

cz-ye/DECENT documentation built on Jan. 25, 2023, 5:57 a.m.